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(D80.4) Selective deficiency of immunoglobulin m [igm]
More details coming soon
230 829 in individuals diagnosis selective deficiency of immunoglobulin m [igm] confirmed
3 237 deaths with diagnosis selective deficiency of immunoglobulin m [igm]
1% mortality rate associated with the disease selective deficiency of immunoglobulin m [igm]
Diagnosis selective deficiency of immunoglobulin m [igm] is diagnosed Men are 29.67% more likely than Women
149 656
Men receive the diagnosis selective deficiency of immunoglobulin m [igm]
1 396 (0.9 %)Died from this diagnosis.
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81 173
Women receive the diagnosis selective deficiency of immunoglobulin m [igm]
1 841 (2.3 %)Died from this diagnosis.
Risk Group for the Disease selective deficiency of immunoglobulin m [igm] - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-89
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 35-39, 85-95+
In Women diagnosis is most often set at age 0-34, 40-84
Disease Features selective deficiency of immunoglobulin m [igm]
Absence or low individual and public risk
Selective deficiency of immunoglobulin m [igm] - what does this mean
Selective deficiency of immunoglobulin m (igm) is an inherited condition that occurs when the body fails to produce enough of the igm antibody, which is responsible for fighting off bacterial infections. this deficiency can make a person more susceptible to infections, as the body is unable to fight them off effectively.
What happens during the disease - selective deficiency of immunoglobulin m [igm]
Selective deficiency of immunoglobulin m (igm) is a rare immunodeficiency disorder caused by a genetic mutation in the gene that codes for the production of igm antibodies. this mutation results in an inability to produce the full range of igm antibodies necessary to protect against bacterial and viral infections. as a result, individuals with this condition are more susceptible to recurrent and prolonged infections, particularly of the respiratory and gastrointestinal tracts.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete Blood Count (CBC)
- Evaluation of serum immunoglobulin levels
- Serum protein electrophoresis
- Antibody titers
- Quantitative immunoglobulin levels
- Flow cytometry
- Immunophenotyping
- Bone marrow biopsy
- Lymph node biopsy
- Genetic testing
Treatment and Medical Assistance
Main goal of the treatment: To increase the level of IgM in the body.
- Administering intravenous immunoglobulin (IVIG) replacement therapy
- Prescribing high-dose oral corticosteroids
- Providing antibiotics to treat infections
- Administering immunomodulatory medications
- Recommending a healthy diet and lifestyle
- Monitoring IgM levels periodically
- Providing genetic counseling
7 Days of Hospitalization Required
126 Hours Required for Outpatient Treatment
Selective deficiency of immunoglobulin m [igm] - Prevention
The best way to prevent selective deficiency of immunoglobulin m [igm] is to maintain a healthy lifestyle, including a balanced diet, regular exercise, and adequate sleep. additionally, it is important to stay up to date on vaccinations, as immunizations can help protect against many diseases that can lead to igm deficiency.